The Southeastern Mustangs took an early lead but Cleveland controlled the game the rest of the way in a 49-13 win at Southeastern last Friday.
Southeastern got on the board midway through the first quarter on a 10- yard run by Avery Jones to take a 6-0 lead.
Cleveland answered on the following possession when Andrew Green hit Parker Gilliland for a 35-yard touchdown. Juan Castro, who was perfect on all seven pat’s, converted and the Panthers led 7-6 after one quarter.
The Cleveland defense tightened up after the first quarter and limited the Mustang offense the rest of the night.
The Panther offense rolled up 405 total yards, led by Green, who completed 4 of 9 passing for 130 yards and a touchdown and rushed for 103 yards and two scores on just nine attempts.
Daquarrious Phillips led the Panthers on the ground with 134 yards and two scores on just 13 carries.
Gilliland caught three passes for 118 yards and a touchdown.
Southeastern got a big night from Jones, who rushed for 81 yards and a pair of touchdowns on 18 carries.
Seth Wadsworth completed 5 of 13 passing for 43 yards and rushed for 60 yards on 14 carries.
Cleveland got a team-high six tackles from Adam Hernandez while Kyle Willis, Nathan Stephens, Austin Hulsey and Hunter Boswell had five stops each. Matthew Lee had a fumble recovery for the Panthers.
Kevin Juhola led the Mustangs with eight tackles while Dylan Thomas, Mitchell Young and Austin Lee had three stops each.
Southeastern (0-2) opens region play with a visit from Addison (2-0) this week while Cleveland (1-0) begins region play by hosting Falkville (0-2).